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Health Benefit Of Red Wine |
Cancer Prevention | FineWine
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Does Red Wine Prevent
Cancer? |
Red
Wine and Cancer Prevention: Fact Sheet
Key Points
(National Cancer Institute)
- Research on the antioxidants found in
red wine has shown that they may help inhibit the development of
certain cancers. (See Question 1)
- Resveratrol has been shown to reduce tumor
incidence in animals by affecting one or more stages of cancer
development. It has been shown to inhibit growth of many types of
cancer cells in culture. (See Question 2)
- Recent evidence from animal studies
suggests this anti-inflammatory compound may be an effective
chemopreventive agent in three stages of the cancer process:
initiation, promotion and progression. (See Question
3)
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Red wine is a rich source of
biologically active phytochemicals, chemicals found in plants.
Particular compounds called polyphenols found in red wine-such as
catechins and resveratrol-are thought to have anti oxidant or anti
cancer properties. |
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1. What are polyphenols and
how do they prevent cancer?
Polyphenols are antioxidant compounds found in the skin and seeds of
grapes. When wine is made from these grapes, the alcohol produced by
the fermentation process dissolves the polyphenols contained in the
skin and seeds. Red wine contains more polyphenols than white wine
because the making of white wine requires the removal of the skins
after the grapes are crushed. The phenols in red wine include catechin,
gallic acid and epicatechin.
Polyphenols have been found to have antioxidant properties.
Antioxidants are substances that protect cells from oxidative damage
caused by molecules called free radicals. These chemicals can damage
important parts of cells, including proteins, membranes and DNA.
Cellular damage caused by free radicals has been implicated in the
development of cancer. Research on the antioxidants found in red wine
has shown that they may help inhibit the development of certain
cancers.
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2. What is resveratrol
and how does it prevent cancer?
Resveratrol is a type of polyphenol called a phytoalexin, a class of
compounds produced as part of a plant's defense system against
disease. It is produced in the plant in response to an invading
fungus, stress, injury, infection or ultraviolet irradiation. Red wine
contains high levels of resveratrol, as do grapes, raspberries,
peanuts and other plants.
FOOD PYRAMID
Resveratrol has been shown to reduce tumor incidence in animals by
affecting one or more stages of cancer development. It has been shown
to inhibit growth of many types of cancer cells in culture. Evidence
also exists that it can reduce inflammation. It also reduces
activation of NF kappa B, a protein produced by the body's immune
system when it is under attack. This protein affects cancer cell
growth and metastasis. Resveratrol is also an antioxidant.
3. What have red wine
studies found?
The cell and animal studies of red wine have examined effects in
several cancers including leukemia, skin, breast and prostate cancers.
Scientists are studying resveratrol to learn more about its cancer
preventive activities. Recent evidence from animal studies suggests
this anti-inflammatory compound may be an effective chemopreventive
agent in three stages of the cancer process: initiation, promotion and
progression.
Research studies published in the
International Journal of Cancer show that drinking a glass of red wine
a day may cut a man's risk of prostate cancer in half and that the
protective effect appears to be strongest against the most aggressive
forms of the disease. It was also seen that men who consumed four or
more 4-ounce glasses of red wine per week have a 60 percent lower
incidence of the more aggressive types of prostate cancer.
However, studies of the association between red wine consumption
and cancer in humans are in their initial stages. Although
consumption of large amounts of alcoholic beverages may increase the
risk of some cancers, there is growing evidence that the health
benefits of red wine are related to its nonalcoholic components.
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Source:
http://www.cancer.gov
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Health Benefit Of Red Wine |
Cancer Prevention
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